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What is the best way to take butyrate?

Jan. 13, 2025

Butyrate: Gut Health Supplement - BodyBio

BodyBio Butyrate is simply butyrate, which is butyric acid + minerals, in our case sodium or calcium/magnesium.. Butyric acid, butyrate and tributyrin are ingredients you may see in other butyrate  supplements &#; same purpose, different characteristics. 

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We use butyric acid aka butanoic acid, a short-chain fatty acid with four carbon atoms at its heart (found naturally in butter, hence its name). As an acid, it has a low pH so we compound it with an alkali (either sodium or calcium/magnesium), a combination that forms a salt + water. At this stage, we no longer have butyric acid, but butyrate, a buffered form of butyric acid.

This formulation is quick to break down once it reaches the gut and immediately gets to work feeding your gut cells. And it provides a sprinkling of extra minerals with either the sodium or calcium/magnesium forms. Sodium butyrate is what is used in almost all scientific studies on butyrate, but some people want to avoid extra sodium intake, so we offer the calcium/magnesium option as an alternative. Both are equally effective.

Tributyrin, which we use in Gut+, is another form of butyrate. Tributyrin is not as quickly broken down in the gut, meaning more will be absorbed into the bloodstream to be used throughout the body. If you&#;re looking for even more of the systemic effects of butyrate, such as metabolic, brain, and immune support, Gut+ may be a better option for you. However, both butyrate and tributyrin will have these systemic effects as well as supply fuel to the gut lining. 

We must also account for the individuality of your unique gut environment and any systemic issues present, so the body may prioritize the use of either butyrate or tributyrin wherever it sees fit

Diets like Paleo and Keto can be deficient in fiber and resistant starch, and therefore, low in butyrate if proper dietary guidelines are not followed. When a Paleo diet is properly followed, an individual should be consuming between 9-12 cups of phytonutrient and fiber-rich plant foods including, green plantains, green bananas, sunchokes, artichokes, cooked and cooled potatoes, etc. in order to produce ample levels of butyrate. The problems arise when individuals focus exclusively on animal protein and fat while neglecting these plant foods/fibers. 

Nine cups of vegetables contain roughly 72 grams of fiber. Remember, we must also consider the health of the individual's microbiome. This factor will also influence butyrate production. 

The ability for your body to synthesize butyrate depends on several factors. Dietary fiber and resistant starch intake are critical, but we also need a plethora of probiotic bacteria in the colon to ferment the fiber that we eat and synthesize it into butyrate, acetate, and propionate (other important SCFAs). The state of the microbiome, the impact of drugs, alcohol, etc. factors into each individual's ability to produce short-chain fatty acids like butyrate. 

Chronic overeating via processed, nutrient-void foods high in energy, fat and sugar is the norm amongst the majority of North Americans. This dietary regimen creates a situation where gut health is greatly compromised and therefore, butyrate production is greatly impaired. One cannot go wrong eating a nutrient-dense diet filled with high quality animal protein and colorful, fiber-rich foods. 

It is important to note that most studies on butyrate are done via butyrate supplementation. Regardless of whether you are making adequate butyrate in the gut, we don't think you can go wrong by supporting your body with a top-up of butyrate through supplementation. Butyrate supplementation has been shown to support a healthy gut inflammation response, improve gut integrity, regulate the immune system, stabilize mood, and improve the gut/brain axis.

Your Gut+ and Butyrate Start Guide - BodyBio

Congratulations! You&#;ve taken the first step toward gut-brain axis support, improved immune system function, and the healthiest BM&#;s of your life

Gut+ is the do-it-all gut health supplement that combines prebiotics and postbiotics to support your natural microbiome, regulate motility, and reduce uncomfortable gut symptoms like gas and bloating.*

But how do you get started taking our newest gut health champion? Here, we&#;ll cover all of your frequently asked questions regarding Gut+, digestive health, and how this new and advanced supplement interacts with Butyrate.

Table of Contents:

  • So I Just Received Gut+ &#; Now What?
  • I&#;m Sensitive to Supplements. Should I Expect Any Side Effects?
  • Can I Open Gut+ Capsules and Take Them With Food or Water?
  • Can I Have a &#;Die Off&#; Reaction with Gut+?
  • Is Gut+ Meant to Replace Butyrate?
  • Do I Take Gut+ with Butyrate?
  • Should I Switch to Gut+ If I Currently Take Butyrate?
  • Do I Need to Take a Probiotic Supplement with Gut+?
  • Can Gut+ Replace My Current Probiotic Supplement?
  • Gut+ vs. Butyrate Major Differences
  • Major Gut+ Benefits vs. Butyrate Benefits
  • Sodium vs. Calcium/Magnesium Butyrate

So I Just Received Gut+ &#; Now What?

First, take a deep breath. Your gut symptoms aren&#;t forever &#; and Gut+ is bringing you one step closer to achieving your health goals.

Take one Gut+ capsule daily with food. Preferably, at breakfast time. This gives your supplement all day to work its magic, saving night hours for (digestive) rest and relaxation. 

If you&#;re already taking a butyrate supplement, you may want to experiment with timing. Gut+ could be your morning supplement and butyrate may fit better into your lunch or dinner schedule. 

Gut+ and butyrate can be taken together, too. However, if you are taking both supplements, we recommend you start slowly by taking them at separate meal times. This gives your body time to adjust to the new protocol without overwhelm.

I&#;m Sensitive to Supplements. Should I Expect Any Side Effects? 

We get it. Your gut is already out of whack and you don&#;t want to make symptoms worse. The good news is, any die-off effects caused by Gut+ are short-lived. And, most people don&#;t experience side effects at all. If you&#;re worried, here are some survival tips to help curb any side effects:

  • Make sure you take Gut+ with a full meal.
  • You can take both Gut+ and butyrate daily. But, if you&#;re sensitive, it&#;s best to work your way up to taking both at once.
  • If you find that Gut+ is too much for your body to handle right now, try taking butyrate first. Butyrate has a lower dosage per capsule and doesn&#;t include Preforpro prebiotics. Once you feel comfortable, you can switch over to Gut+.
  • If your heart is set on Gut+, simply lower the dosage and take it once every two days until your body gets used to it. 

Are you experiencing side effects? We&#;ve found that any side effects (usually mild constipation) resolve themselves after a few days.

Can I Open Gut+ Capsules and Take Them With Food or Water?

Gut+ is carefully formulated for optimal absorption and bioavailability in a one capsule dose. For this reason, we don&#;t recommend altering the capsules in any way or opening them.

The company is the world’s best butyric acid benefits supplier. We are your one-stop shop for all needs. Our staff are highly-specialized and will help you find the product you need.

Can I Have a &#;Die Off&#; Reaction with Gut+?

Yep, it&#;s totally possible to have a detox or &#;die off&#; reaction when taking Gut+, as it is with any supplement, especially for those who are sensitive. However, it&#;s unlikely. Flu-like symptoms, headache, or fatigue are typically a sign that you are killing off a pathogen and/or rebalancing the microbiome. When this happens, you may need to support your drainage pathways. 

Here are some ways you can support your body through the detox process: 

  • Liposomal glutathione
  • NAC
  • Milk thistle
  • Dry brushing
  • Infrared sauna use
  • Exercise/movement 
  • Rebounding (trampoline jumping is great for your lymphatic system!)
  • Castor oil packs
  • Liquid minerals for energy
  • Lymphatic massage
  • Support your brain and cell membranes with BodyBio PC

People with a complicated medical history (chemical sensitivity, mold exposure, parasites, Lyme disease, SIBO, glyphosate toxicity, etc.) are generally more likely to experience a Herxheimer reaction when taking Gut+, but it isn&#;t guaranteed. 

If you feel anxious about beginning Gut+, take a moment to evaluate your drainage pathways. Do you struggle to sweat? Do you poop daily? Do you digest fats correctly? It may be helpful to make some progress on these blockage issues before beginning Gut+. However, Gut+ may also be the catalyst to improving some of these issues by rebalancing your microbiome. This is an individual process, so evaluate your situation and proceed accordingly. 

What are PreforPro Prebiotics?

We believe Preforpro prebiotics are the most scientifically advanced way to gently curb dysbiosis and rebalance your gut. But what are they exactly? Preforpro is a bacteriophage that gently eliminates unwanted bacteria from the gut &#; leaving room for healthy bacteria to grow and flourish. The bacteriophage prebiotics are designed to support your healthy gut bacteria without causing the bloating and gas that fiber-based prebiotics sometimes do.

Is Gut+ Meant to Replace Butyrate? 

Since Gut+ contains highly absorbable tributyrin, it can be used as a replacement for your everyday butyrate supplement. Think of it as our new state-of-the-art butyrate option. However, Gut+ doesn&#;t have to replace butyrate if butyrate is working perfectly fine for you now. Some people also find added benefits in taking both supplements daily.

Do I Take Gut+ with Butyrate? 

We recommend you evaluate your gut health status before replacing butyrate with Gut+. If you have a number of digestive complaints, it may be beneficial to take both supplements daily. If symptoms are mild or you are looking to maintain healthy gut status, you can probably get away with Gut+ alone. One way to evaluate your gut health is to take a test like the Thorne Onegevity Gut Test

Should I Switch to Gut+ If I Currently Take Butyrate?

If you only have the budget or capacity for one gut supplement, it may be beneficial to switch to Gut+. This is because Gut+ includes Preforpro prebiotics and postbiotics and is unlike any other gut supplement on the market. Essentially, it&#;s a broader approach to digestive health than taking butyrate alone. 

Everyone reacts differently to supplements, so we recommend you try Gut+ and butyrate for up to 1-3 months each to evaluate the benefits. Then, choose the one that works best for you.

Do I Need to Take a Probiotic Supplement with Gut+?

Broad-spectrum probiotics aren&#;t as effective as clever marketing wants you to believe. In fact, 66% of BodyBio customers said their probiotic supplement had little to no effect on their overall gut health. Yikes!

Instead of probiotics, Gut+ uses prebiotics and postbiotics to improve gut health. These provide fuel and support for the healthy bacteria that are already growing in your gut &#; allowing it to prosper naturally. 

No, you don&#;t necessarily need to take a probiotic supplement in addition to Gut+. If you have a probiotic you really love, by all means, keep taking it. But if your probiotic supplement doesn&#;t provide any results, it&#;s time to ditch it and watch Gut+ do its magic.

Can Gut+ Replace My Current Probiotic Supplement?

Your microbiome is as unique as your fingerprint. It&#;s made up of trillions of microscopic bacteria that can impact your digestion for good or bad. When you take a broad-spectrum probiotic, your body doesn&#;t necessarily have the fuel (prebiotics and postbiotics) to support it. And, you&#;re shooting in the dark because you don&#;t actually know what bacterial strains your body needs. 

We created Gut+ as a probiotic replacement. Its goal is to work alongside your unique microbiome &#; instead of trying to replace it with unknown probiotics. Prebiotics and postbiotics provide fuel for your natural microbiome to thrive.

Gut+ vs. Butyrate Major Differences

How about a side-by-side comparison of Gut+ versus butyrate? We&#;ve got you. Here, you can evaluate the differences between these two cutting-edge supplements and decide which one is best for you.

Major Gut+ Benefits vs. Butyrate Benefits

In addition to the benefits listed in our chart above, there are a few other things you should know about Gut+ and butyrate for gut health

Gut+ is designed as an all-in-one gut health supplement. You no longer have to sort through dozens of pills each morning hoping that one of them will take care of your gut dysbiosis. Preforpro bacteriophage prebiotics and ultra absorbable tributyrin combine for full body benefits like blood sugar regulation, detox, digestion, and brain support. Think of it as a more advanced form of our trusted butyrate supplement. 

Read more: What is Gut+? 

BodyBio Butyrate has been recommended by practitioners for decades. It contains just butyrate and minerals (sodium or calcium and magnesium) for a simple approach to healing gut permeability. It focuses on gut lining integrity, supports a healthy inflammatory response, and supports blood sugar balance.  

Read more: What is Butyrate?

Sodium vs. Calcium/Magnesium Butyrate

Curious to know more about the benefits of butyrate? We offer two kinds of butyrate supplements: calcium and magnesium butyrate and sodium butyrate. One of our most common questions is: which kind is best for me? Check out this blog post for answers.

Are you interested in learning more about isobutyric acid manufacturer? Contact us today to secure an expert consultation!

We Want to Heal Digestive Distress Worldwide

Gut dysbiosis is no joke &#; and it&#;s on the rise. Around 60 to 70 million people suffer from digestive diseases worldwide. One recent US-based study suggests that almost 2 out of 3 people suffer from gut problems.

Our supplements have been trusted by practitioners for decades &#; and best of all, they&#;ve helped hundreds of people remember what life was like before gut symptoms. If you&#;ve tried everything to heal your gut, without any results, then we created Gut+ for you.

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