Mebendazole API Manufacturers | GMP-Certified Suppliers

Looking for Mebendazole API -39-7?

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Here you will find a list of producers, manufacturers and distributors of Mebendazole. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.

API | Excipient name:

Mebendazole 

Synonyms:

MBDZ , Mebendazol , Mebendazol , Mebendazolum , Vermox , Mebendazole Polymorph C  

Cas Number:

-39-7 

DrugBank number:

DB 

Unique Ingredient Identifier:

81G6I5V05I

About Mebendazole

Here is a short description about Mebendazole. A benzimidazole that acts by interfering with carbohydrate metabolism and inhibiting polymerization of microtubules.

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You can ask the supplier about all relevant certificates for the product such as CoA, Safety Data Sheet and DMF.

Mebendazole is a type of Anthelmintics

Anthelmintics belong to the pharmaceutical API subcategory used in the treatment of parasitic infections caused by helminths, commonly known as worms. These parasitic infections can affect various parts of the body, including the intestines, liver, and lungs. Anthelmintics act by either paralyzing or killing the helminths, thereby eliminating the infection.

There are different classes of anthelmintics, each targeting specific types of helminths. The benzimidazoles class includes compounds like albendazole and mebendazole, which disrupt the energy metabolism of the worms, leading to their paralysis and eventual death. Another class is the avermectins, which includes ivermectin and moxidectin. These compounds work by affecting the neurotransmitter functions in the worms, resulting in paralysis and death.

Anthelmintics are available in various formulations, including tablets, suspensions, and injectables, allowing for convenient administration to patients. Depending on the type and severity of the infection, the duration of treatment may vary.

When using anthelmintics, it is crucial to follow the prescribed dosage and duration to ensure the effective elimination of the parasitic infection. However, as with any medication, there may be potential side effects, such as gastrointestinal disturbances or allergic reactions, which should be monitored.

In conclusion, anthelmintics are a vital class of pharmaceutical APIs used to combat parasitic infections caused by helminths. Their targeted action and diverse range of formulations make them an essential tool in the fight against these debilitating conditions.

Mebendazole (Anthelmintics), classified under Antiparasitics

Antiparasitics are a category of pharmaceutical Active Pharmaceutical Ingredients (APIs) that are used to combat parasitic infections in humans and animals. These APIs play a crucial role in the field of medicine and veterinary care by targeting and eliminating various parasites, such as protozoa, helminths, and ectoparasites.

The use of antiparasitics is essential in preventing and treating parasitic diseases, which can cause significant health issues and even be life-threatening. These APIs work by interfering with the parasite's vital biological processes, such as reproduction, metabolism, and survival mechanisms.

Pharmaceutical companies develop and manufacture a wide range of antiparasitic APIs to cater to different parasitic infections. Some common examples of antiparasitics include anthelmintics (used against intestinal worms), antimalarials (used to treat malaria), and ectoparasiticides (used to control external parasites like ticks and fleas).

The development of antiparasitic APIs requires rigorous research, including the identification of suitable targets within the parasite's biology and the formulation of effective chemical compounds. Safety and efficacy are paramount in the manufacturing of antiparasitics, ensuring that they effectively combat the targeted parasites while minimizing adverse effects on the host.

Overall, antiparasitics are vital tools in the fight against parasitic infections, benefiting both human and animal health. Through ongoing research and development, the pharmaceutical industry continues to innovate and improve antiparasitic APIs, contributing to the advancement of healthcare and the well-being of individuals and their animal companions.

Mebendazole manufacturers | traders | suppliers

We have 10 companies offering Mebendazole produced in 4 different countries.

Get in contact with the supplier of your choice:

• Chr. Olesen Group from Denmark, product country of origin China
• Xi'an ZB Biotech Co., Ltd from China, product country of origin China
• LGM Pharma from United States, product country of origin World
• TIEFENBACHER API + Ingredients from Germany, product country of origin Unknown
• Aarambh Life Science from India, product country of origin India
• Aquatic Remedies Pvt Ltd from India, product country of origin India
• KA Malle Pharmaceuticals from India, product country of origin India
• Cipla from India, product country of origin India
• MSN Life Sciences from India, product country of origin India
• Optimus Drugs Pvt Ltd from India, product country of origin India

Let the supplier know whether you are looking for a product with a specific monograph such as EP (Ph. Eur.), USP, JP, BP or another quality. Or, whether you are looking for hydrochloride (HCl), anhydricum, base, micronisatum or a specific purity.

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CNN

The US Food and Drug Administration has settled a lawsuit over some of its posts about ivermectin, including what may have been one of its more popular pandemic-era social media campaigns.

In August , to discourage people from using ivermectin to prevent or treat Covid-19, the FDA tweeted &#;You are not a horse. You are not a cow. Serious y&#;all. Stop It.&#; and posted a similar message on Instagram. The tweet got nearly 106,000 likes.

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The antiparasitic drug, which is prescribed to treat neglected tropical diseases in humans like river blindness and scabies, can also be bought over-the-counter at livestock supply centers to help deworm animals such as horses and cows.

Some conservative outlets touted the drug as safe and effective against Covid even though the FDA and the World Health Organization encouraged people not to use it, saying it was ineffective against Covid and could even be dangerous if someone took too much.

Some conservative media personalities and lawmakers said information about the effectiveness of ivermectin was being downplayed because of its low price. It was also praised as a &#;miracle drug&#; by Dr. Pierre Kory, a pulmonologist and president of the Frontline COVID-19 Critical Care Alliance, who testified at a US Senate committee hearing in December . Even popular podcaster Joe Rogan, who took the drug along with several other medicines after testing positive for Covid, got into a spirited discussion with CNN Chief Medical Correspondent Dr. Sanjay Gupta about it at the time.

In August , the US Centers for Disease Control and Prevention sent a health advisory warning doctors and the public about the &#;rapid increase&#; in prescriptions for ivermectin and an increase in reports to poison centers about severe illness caused by the drug. Some people who took higher than recommended doses or used the animal formulation developed neurological symptoms, and some were hospitalized, studies show.

The FDA said in an to CNN on Wednesday that it &#;has chosen to resolve this lawsuit rather than continuing to litigate over statements that are between two and nearly four years old.&#;

The agency added that it has &#;not admitted any violation of law or any wrongdoing, disagrees with the plaintiffs&#; allegation that the agency exceeded its authority in issuing the statements challenged in the lawsuit, and stands by its authority to communicate with the public regarding the products it regulates.

&#;FDA has not changed its position that currently available clinical trial data do not demonstrate that ivermectin is effective against COVID-19. The agency has not authorized or approved ivermectin for use in preventing or treating COVID-19.&#;

The lawsuit was filed in June by Drs. Rober Apter, Mary Talley Bowden and Paul Marik against the FDA, the US Department of Health and Human Services and their leaders. It claimed that the agencies were interfering with their ability to practice medicine by overstepping their authority and violating the Administrative Procedure Act.

The lawsuit says the doctors &#;have been pressured, unable to prescribe medication, and threatened with or subjected to professional discipline.&#;

Bowden, for example, began recommending ivermectin to treat Covid in early and, according to the suit, was &#;derided by Houston Methodist Hospital and forced to resign her privileges there as a result.&#; Marik was forced to resign his positions at Eastern Virginia Medical School and Sentara Norfolk General Hospital for promoting the use of ivermectin after the FDA&#;s actions, according to the lawsuit.

The FDA told CNN on Wednesday that the lawsuit challenged its authority to issue a Consumer Update in March , several tweets and other social media posts from and that linked to the article, and two FAQs posted in , which the FDA said have &#;already been retired from the agency&#;s website.&#; The posts and other materials will be removed and archived as required by law.

Initially, the FDA claimed sovereign immunity, and a lower court judge in Texas dismissed the suit. The doctors appealed the case to the 5th Circuit, which reinstated the lawsuit last year, and its judges heard arguments last month.

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Lawyers representing the doctors said in a statement posted on Boyden Gray PLLC&#;s website that the FDA &#;has agreed to delete its most viral social media campaign of all time&#; and claimed that the FDA&#;s advice about the off-label use of ivermectin was &#;unlawful.&#;

&#;Today&#;s settlement with the FDA is a major win for the doctor-patient relationship,&#; Marik said in the statement. &#;It vindicates our position that the FDA overstepped its regulatory authority by trying to dictate appropriate medical care.&#;

Independent presidential candidate Robert F. Kennedy Jr. posted on X, formerly Twitter, on Wednesday that the FDA &#;is biased against many low-cost, generic, and/or natural therapies&#; and implied that the FDA is in league with the pharmaceutical industry.

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